148 record(s) found in the location "" (multi-year projects are grouped):
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Influenza A H1N1 (Swine Flu) ICU Study
Principal Investigator: Kandola, Kami
Licensed Year(s): 2010
Summary: Primary objective: To describe the presenting patient characteristics, organ dysfunction, clinical outcomes and resource needs of influenza-H1N1-related critical illness and acute lung injury among children and adults in Canada. Our primary endpoint will be survival and the secondary endpoint will be critical care-free days, both at 90 days after onset of critical illness. Secondary main object...


Should Newborn Screening be Initiated in the Northwest Territories for Mild CPT1 (Carnitine Palmitoyl Transferase-1) Deficiency?
Principal Investigator: Arbour, Laura
Licensed Year(s): 2010 2009 2008 2007
Summary: The goals of this study are: 1. To determine the NWT-wide and regional specific prevalence of a genetic change, known as the P479L variant, associated with mild Carnitine Palmitoyl Transferase-1 (CPT1) Deficiency. 2. To determine the prevalence of the P479L variant in infants who died unexpectedly (from infection or unknown causes) in NWT. 3. To determine whether the P479L variant is associated...


Do tailored messages promote evidence-informed decision making in breast cancer prevention?
Principal Investigator: Dobbins, Maureen
Licensed Year(s): 2010
Summary: The objectives of this study are: 1) To evaluate a knowledge transfer and exchange (KTE) strategy to improve the provision of public health services for breast cancer prevention and early detection and 2) to determine if tailored messages (active knowledge transfer) are more effective than access to a website housing rigorous systematic reviews in breast cancer prevention and early detection (pass...


Examining DNA Fingerprinting as an Epidemiology Tool in the Northwest Territories
Principal Investigator: Case, Cheryl A
Licensed Year(s): 2010
Summary: The questions posed are: 1. Did genotyping identify unknown TB contacts or transmissions among cases studied? Examination of the genotype of each isolate of M. tuberculosis from reported cases in the NWT may identify epidemiological links among the studied cases not previously identified through conventional contact tracing. The study will quantitatively review epidemiological links established ...


Cultural Safety: Respecting Aboriginal Perspectives in a Health Care Setting
Principal Investigator: Hall, Karen
Licensed Year(s): 2009
Summary: The goal of this research is to help Yellowknife Health and Social Services Authority become a leader and model for the integration of culturally safe health care practices. This study also serves to increase health care workers' sensitivity to many of the cultural issues that are specific to the Aboriginal populations living in Yellowknife, thus raising awareness of the importance of fostering an...


Youth and Tobacco Studies with the Yellowknives Dene First Nations
Principal Investigator: Jardine, Cindy G.
Licensed Year(s): 2009
Summary: This licence is being issued for the scientific research application No. 1048. This research project seeks to better understand the factors and conditions that lead youth to decide to start, or not start, smoking. It will focus on youth within the Yellowknives Dene First Nation. A secondary objective is to expose students to the research process and develop research skills. The project is being...


Hypertonic Saline for the Treatment of Bronchiolitis
Principal Investigator: Hoechsmann, Alexander
Licensed Year(s): 2009
Summary: This licence was issued for the scientific research application No. 949. This study is designed to determine whether nebulized hypertonic saline is an effective treatment for bronchiolitis in the northern Canadian population. Infants presenting to Stanton Emergency will be randomly assigned standard treatment for bronchiolitis plus placebo (nebulized normal saline) or standard treatment plus...


The Prevalence of Human Papillomavirus and Its Impact on Cervical Dysplasia in the Northwest Territories: Component II
Principal Investigator: Mao, Yang
Licensed Year(s): 2009 2008
Summary: This license has been issued for the scientific research application #938. The objectives of this study are: 1. examine the impact of social, demographic, lifestyle and behaviour factors to the HPV infection prevalence in NWT; 2. establish the baseline for evaluating the HPV vaccine program in future. The study population includes: women from the following 12 communities: Behchoko (Rae-Edzo)...


Prevalence, determinants and impact of arthritis and other chronic conditions in the First Nations populations of Canada, Yukon, and the Northwest Territories
Principal Investigator: Young, Kue
Licensed Year(s): 2008
Summary: This license has been issued for the scientific research application #957. The objectives of this study are to: 1) determine prevalence and identify risk factors of arthritis and other chronic conditions among First Nations in the Yukon, Northwest Territories and Canada; 2) assess the impact of these conditions on health, well-being and access to health services; 3) enhance the capacity of the ...


Risk factors associated with a tuberculosis (TB) outbreak in a Canadian Northern population
Principal Investigator: Schreiber, Yoko S
Licensed Year(s): 2008
Summary: This license has been issued for the scientific research application #952. The purpose of this study is to determine the risk factors associated with the high rate of TB transmission and incidence leading to the 1997 TB outbreak. This study will examine issues with delay in diagnosis and contact tracing, as well as identifying environmental, behavioural and innate risk factors associated with ...


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