The Aklavik H. pylori Project

Regions: Inuvialuit Settlement Region, Gwich'in Settlement Area

Tags: health, public health

Principal Investigator: Goodman, Karen J (16)
Licence Number: 14251
Organization: University of Alberta
Licensed Year(s): 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007
Issued: Sep 17, 2007
Project Team: Billie Archie, Jerome Gordon, Rachel Munday, Susan Chatwood, Leah Seaman, John Morse, Andre Corriveau, Crystal Lennie, Robert Bailey, Robert Rennie, Carl Phillips, Christopher Fletcher, Joanne Simala-Grant, Diane Taylor, Monika Keelan, Sander van Zanten, Hien Huynh, Justin Cheung, Richard Fedorak

Objective(s): To develop a comprehensive approach to investigating community health problems related to H. pylori infection in NWT communities and to identify public health solutions that respond to community health care needs as perceived by community members and health authorities.

Project Description: The long-term objectives of this research are to develop a comprehensive approach to investigating community health problems related to H. pylori infection in NWT communities and to identify public health solutions that respond to community health care needs as perceived by community members and health authorities. As a starting point, a project will be carried out in the Hamlet of Aklavik, with the following aims, which could be expanded later to culturally diverse NWT communities: Phase I Conduct a community-based investigation of H. pylori infection to test residents for H. pylori infection and collect data on related clinical, social, and environmental factors. Phase II Using endoscopy to examine the stomach, estimate the prevalence of visible abnormalities, and obtain biopsies to: 1) characterize inflammation and abnormal changes; 2) estimate the prevalence of bacterial strains that are resistant to antibiotics or associated with more severe disease. Phase III Conduct a trial to identify effective treatment and follow those treated long-term to identify factors associated with treatment failure and reinfection. Phase IV Conduct policy analysis to develop cost-effective strategies for management of H. pylori infection; inform community members of the research results in a manner that helps them understand how they can use this information to safeguard health Community participation in the research process and sharing resulting knowledge with community members are cornerstones of accepted standards for conducting research in Aboriginal communities. Because community participation and knowledge transfer are mutually supportive, these dimensions of the research will operate from start to finish. As information is generated by the research, activities will be developed to inform the community of the results and help them understand how to use this information to safeguard individual and community health. The Study Planning Committee will help with the development of communication media for sharing information with the community. Particular consideration will be given to targeting groups such as Youth and Elders. This research addresses a health priority identified by residents of Aklavik, who are aware that H. pylori infection poses a health threat to them. NWT health officials have heard their concerns and support this project so they can find solutions to this community health problem. A complete description of the methodology and other details about this project are available from the principal investigator, Dr. Karen Goodman, or online on your ARI website account (login at the community portal at www.nwtresearch.com/polar/). Fieldwork will be conducted from September 17 to December 31, 2007 in Aklavik, NT.